December 7, 2011 – 9:43 am
Salisbury, UK, 7th December 2011: NanoSight, leading manufacturers of unique nanoparticle characterization technology, describes how the Nano Chemistry group at DTU Copenhagen is utilizing nanoparticle tracking analysis, NTA, in its research and teaching programs.
The NanoChemistry group at the Department of Chemistry at DTU in Kongens Lyngby near Copenhagen, is led by Professor Jens Ulstrup.
Chemistry at the nanoscale deals with the observation and manipulation of Nature’s tiniest chemical building blocks, and with the design and exploitation of new properties that arise from nanoscale objects. The NanoChemistrty group at DTU Chemistry uses new and untraditional technologies which has helped us to open a whole new world of “ultra-small” chemical and physicochemical systems of great importance for future technology. One of the current projects dealing with nanoparticles in solution is the SAMENS project.
The main objective of NanoChemistry’s SAMENS project (saccharide-based approach to metallic nanostructure synthesis) is to develop methods for the preparation of novel exciting nanostructures. These include very small, (i.e. less than a few nanometers) metallic and metal oxide nanoparticles, core-shell hetero-nanostructures of metals and metal oxides and highly anisotropic nanostructures. These are thoroughly characterized by a variety of methods and applied in electrochemistry and electrocatalysis. The research is built on a strong “green” foundation (i.e. harmless chemicals, aqueous environment and mild synthesis conditions) with constant efforts also within nanotoxicology. The properties of the nanostructures depend strongly on their size and shape, so it is critical that we have precise knowledge about these parameters. Read More »
December 6, 2011 – 4:35 pm
Salisbury, UK, 6th December 2011: NanoSight, leading manufacturers of unique nanoparticle characterization technology, are winners of this year’s Technology World’s 2011 Business Innovation Award in the category of Energy & Environment. These annual awards are sponsored by the PA Consulting Group.
Now in their 4th year, the Business Innovation Awards showcase the very best of British innovation. After receiving a record number of entries, NanoSight has been named winners in the Energy & Environment category in recognition of their position as world leading providers of instruments for the optical detection and real time analysis of sub-micron particles.
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November 10, 2011 – 2:58 pm
Salisbury, UK, 9th November 2011: NanoSight, leading manufacturers of unique nanoparticle characterization technology, are in the Deloitte 2011 Fast 50 list of the fastest growing technology companies in the UK. In the world of biotech, NanoSight has made it to number one nationwide and overall is the fastest growing of all technology companies in the South West and Wales region of the UK.
NanoSight has been ranked in the Deloitte 2011 UK Technology Fast 50, which recognises the 50 fastest-growing technology companies in the UK. The company has also been named as a winner in the Technology Fast 500 EMEA 2011 rankings, which recognises the 500 fastest-growing technology companies across Europe, the Middle East and Africa. Both programmes are based on percentage revenue growth over the last five years.
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October 5, 2011 – 11:29 am
June 2011 has seen the total number of peer-reviewed user publications and citations reach 250. This number has been rising rapidly with the most recent 150 papers appearing in less than a year. Starting with this issue of NanoTrail, we will be highlighting three papers and providing links to where you may view them in more detail.
As NanoSight founder and CTO, Bob Carr, says, third party papers is the best proof for a new method being accepted by the world at large. Our long list which has been generated so rapidly provides maximum credibility and widespread international endorsement of our technology.
The full list will continue to be updated on our web site where the papers are grouped by application: toxicity & the environment, assessment of NTA, drug delivery & micelles, exosomes, pharma & vaccines, nanoparticle production and materials/miscellaneous. The link is here. Read More »
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Posted in General
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Tagged bob carr, cheska gillespie, darren edwards, gothenburg, houston, jani tuoriniemi, julian a gallego urrea, martin hassellhov, Nanoparticle Tracking Analysis, NanoSight, nta, peter g vekilov, peter halling, strathclyde, third party papers, vassiliy lubchenko, ye li
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October 4, 2011 – 2:27 pm
In an article written by Dr K John Morrow and published in the leading US publication, Genetic Engineeringand Biotechnology News, NanoSight user, Alla Polozova, a senior scientist in analytical biochemistry at MedImmune talks about her work.
Delineating Protein Particles
Contending with various forms of junk that arise during protein purification requires a number of different strategies. Alla Polozova, a senior scientist in analytical biochemistry at MedImmune, described her approach to detecting and eliminating the variety of particulate contaminants in protein solutions that harry investigators. Read More »
October 3, 2011 – 1:30 pm
We are pleased to report that the School of Medicine at the University of St Andrews is using nanoparticle tracking analysis to characterize exosome behaviour
Dr Simon Powis and his colleagues at the University of St Andrews are working to understand how a set of 
molecules involved in the immune system’s defence against intracellular pathogens function. These molecules are called major histocompatibility complex (MHC) class I molecules, and they are expressed on almost every cell in the body. Their relevance to medicine is most commonly known because they are one of the key sets of genes that have to be closely matched when an organ transplant is made, otherwise the transplant can be rejected. It is now known that their precise role in the normal immune system is to bind small fragments of degraded viral proteins which they display to T lymphocytes of the immune system. This allows the specific detection of ‘foreign’ proteins, i.e. from potential pathogens, and allows the immune system to specifically detect and kill infected cells, whilst leaving a neighbouring uninfected cell alone. In addition, there is one fascinating autoimmune disease closely associated with a particular type of MHC class I molecule. Over 90% of patients with a type of inflammatory arthritis called ankylosing spondylitis which affects the spine, expresses one specific type of MHC class I molecule called HLA-B27. The link between this arthritic condition and HLA-B27 has been known for almost 40 years, but the disease mechanism and how HLA-B27 is involved is yet to be understood. Read More »
September 30, 2011 – 11:52 am
We are happy to report the publication in one of the most cited peer reviewed journals in nanoscience and nanotechnology, NanoMedicine. It has been written by a group of researchers from the Nuffield Department of Obstetrics & Gynaecology, Oxford University.
The rapidly growing field of exosomes and microvesicles is published online.
Titled “Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis,” it has been authored by a team led by Professors Ian Sargent and Paul Harrison. It is described below. Read More »
September 29, 2011 – 11:32 am
“Disruptive” is the description that technology watchers apply to the “new” whose benefits are great enough for users to reject current products or techniques and adopt that “new”. “Disruptive” has become a watchword for technology success. Looking back at the development of Nanoparticle Tracking Analysis, what started as an “interesting image” in 2005 has grown into a proven, multiparameter characterization method today. We have added concentration measurement, Zeta potential and fluorescence capabilities, an indication of shape (or at least of non-sphericity) and clues to composition, as differentiated by refractive index. All this, on particle–by-particle basis, supported by visual observation, certainly puts clear blue water between NTA and other characterization technologies. That said, describing the technology is hardly an objective measure of “disruptiveness.” It was one of our senior scientific advisors who recently suggested a method of gauging disruptiveness within our sector of instrumentation technologies; we should look at the growth rate in papers citing the technology. Read More »