NanoSight's Technology

Nanoparticle Tracking Analysis (NTA) is a relatively new technique for the rapid, direct and real-time visualization of nanoparticles in a liquid. Based on laser-illuminated optical microscopy, nanoparticles are seen as light-scattering centers moving under Brownian motion. A video of the movement of each particle is analyzed on a frame-by-frame basis and the particle's size is established from an analysis of the average speed of movement. Because each particle is measured separately, it is possible to measure particle size and relative light-scattering intensity at the same time, allowing better resolution of mixtures of different particle sizes or types within a sample than would be possible with conventional dynamic light-scattering techniques such as photon correlation spectroscopy. Importantly, particle count or concentration are also measured.

 

For more information click here to download NanoSight's NTA mini-review.

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